Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565372 | 0.91 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL10565455 | 0.90 | GAA (0.43) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL10565848 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10569523 | 0.85 | GAA (0.51) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL10566127 | 0.84 | SMN1; SMN2 (0.46) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL11041438 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL10567289 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10568375 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL11040008 | 0.76 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL10969707 | 0.75 | TP53 (0.41) | ALDH1A1ACLYMEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070698-B1 | HERBICIDAL INDOLE SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | claimed |
| EP-0070698-A1 | Herbicidal indole sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-26 | — | — | EP | claimed |
| US-4836846-A | PRE/POST EMERGENCE; WEEDS, GRASSES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| US-4764610-A | Herbicidal indole sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0070698-B1 | HERBICIDAL INDOLE SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0070698-A1 | Herbicidal indole sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |