Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566127 | 0.94 | SMN1; SMN2 (0.46) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL10565848 | 0.89 | ALDH1A1 (0.45) | GAAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10565455 | 0.87 | GAA (0.43) | GAAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10568375 | 0.87 | KDM4E (0.51) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL10567657 | 0.85 | KDM4E (0.42) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10565372 | 0.85 | ALDH1A1 (0.42) | GAAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL11043791 | 0.84 | GAA (0.49) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL10567289 | 0.81 | ALDH1A1 (0.56) | GAAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10974258 | 0.79 | GAA (0.44) | GAAMAPTTP53GLAALDH1A1 | |
| SCHEMBL10984018 | 0.77 | GAA (0.60) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070698-B1 | HERBICIDAL INDOLE SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | claimed |
| EP-0070698-A1 | Herbicidal indole sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-26 | — | — | EP | claimed |
| US-4836846-A | PRE/POST EMERGENCE; WEEDS, GRASSES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| US-4764610-A | Herbicidal indole sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0070698-B1 | HERBICIDAL INDOLE SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | disclosed |