Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754129 | 0.84 | CARM1 (0.55) | HTR2AHTR2CCYP2D6PRMT3CARM1 | |
| SCHEMBL10459141 | 0.82 | HTR2A (0.53) | HTR2AHTR2CHTR7CYP2D6HTR6 | |
| SCHEMBL10460414 | 0.82 | HTR2A (0.50) | HTR2AHTR2CHTR7CYP2D6HTR6 | |
| SCHEMBL9872541 | 0.81 | CYP2D6 (0.53) | HTR2AHTR2CHTR7CYP2D6HTR6 | |
| SCHEMBL10460536 | 0.79 | HTR2A (0.58) | HTR2A | |
| SCHEMBL8742998 | 0.79 | HTR2A (0.50) | HTR2AHTR2CHTR7CYP2D6HTR6 | |
| SCHEMBL9252180 | 0.78 | SLC6A3 (0.64) | HTR2AHTR7CYP2D6HTR6SLC6A3 | |
| SCHEMBL10558204 | 0.77 | KDM4E (0.57) | HTR2AHTR7CYP2D6HTR6SLC6A3 | |
| SCHEMBL10568624 | 0.77 | HTR2A (0.45) | HTR2AHTR2CHTR7CYP2D6HTR6 | |
| SCHEMBL10560791 | 0.76 | DRD2 (0.57) | HTR2AHTR7HTR6SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853387-A | Piperidine derivatives, and their application in therapy | SYNTHELABO (FR) | 1989-08-01 | — | — | US | disclosed |