Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567673 | 0.81 | HTR2A (0.52) | CYP2D6HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL7330054 | 0.81 | CYP2D6 (0.80) | CYP2D6HTR2AMEN1CHRM2HTR1A | |
| SCHEMBL9872721 | 0.79 | CYP2D6 (0.47) | CYP2D6HTR2AHTR2CHTR7OPRM1 | |
| SCHEMBL10459141 | 0.79 | HTR2A (0.53) | CYP2D6HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL7640547 | 0.79 | DRD2 (0.58) | CYP2D6HTR2AHTR7PRCPHTR6 | |
| SCHEMBL11712337 | 0.79 | SLC6A3 (0.50) | CYP2D6KMT2AKCNH2CACNA1B | |
| Oxalic Acid SCHEMBL10557086 | 0.78 | CYP2D6 (0.53) | CYP2D6HTR2AHTR2CHTR7MEN1 | |
| Hydrochloric Acid SCHEMBL7329135 | 0.78 | HTR2A (0.63) | CYP2D6HTR2AHTR2CHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7658850 | 0.78 | DRD2 (0.57) | CYP2D6HTR2AHTR7PRCPHTR6 | |
| SCHEMBL10556073 | 0.77 | HRH3 (0.55) | CYP2D6HTR2AHTR1ADRD1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |