Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.43 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566831 | 0.85 | GAA (0.41) | RAB9ASMN1; SMN2ALDH1A1GAACHRM5 | |
| SCHEMBL10670734 | 0.81 | CHRM5 (0.42) | RAB9ASMN1; SMN2ALDH1A1GAACHRM5 | |
| SCHEMBL14817119 | 0.81 | RAB9A (0.45) | RAB9AGAAPTGS2NPC1LMNA | |
| SCHEMBL10669577 | 0.80 | NPSR1 (0.59) | RAB9AALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL6341114 | 0.79 | CSNK1G1 (0.43) | CDC7PLK4DAPK3ROCK2CHEK2 | |
| SCHEMBL10572176 | 0.78 | ALDH1A1 (0.44) | CDC7PLK4DAPK3ROCK2CHEK2 | |
| SCHEMBL9239773 | 0.77 | MEN1 (0.46) | RAB9ASMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL20628911 | 0.75 | CHRM5 (0.46) | RAB9ASMN1; SMN2ALDH1A1CHRM5CHKA | |
| SCHEMBL7742836 | 0.75 | HCAR2 (0.46) | RAB9ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL12593354 | 0.74 | CHRM5 (0.50) | RAB9ASMN1; SMN2ALDH1A1GAACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855308-A | Method of treating senile cognitive decline with N'-substituted aminopyridine adrenergic agents | WARNER-LAMBERT COMPANY (US) | 1989-08-08 | — | — | US | claimed |
| US-4855308-A | Method of treating senile cognitive decline with N'-substituted aminopyridine adrenergic agents | WARNER-LAMBERT COMPANY (US) | 1989-08-08 | — | — | US | disclosed |