SCHEMBL9239773

SCHEMBL9239773

CC(=O)N(c1ccc(C)cc1)c1cccc(N(C(C)=O)c2ccc(C)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
TSHR P16473 2/20 0.46
KMT2A Q03164 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.44
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B1 P14061 2/20 0.39
HSD17B2 P37059 2/20 0.39
PTGIR P43119 1/20 0.38
LMNA P02545 2/20 0.38
NPC1 O15118 2/20 0.38
APAF1 O14727 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HCRTR2 O43614 1/20 0.38
TSPO P30536 1/20 0.37
KEAP1 Q14145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1947881 0.85 LMNA (0.48) MEN1TSHRKMT2AALDH1A1RAB9A
SCHEMBL8044893 0.79 NPSR1 (0.61) MEN1TSHRKMT2ATRPM8ALDH1A1
SCHEMBL14817119 0.78 RAB9A (0.45) TSHRKMT2ATRPM8RAB9ALMNA
SCHEMBL10567778 0.77 CDC7 (0.43) TSHRTRPM8ALDH1A1RAB9ASMN1; SMN2
SCHEMBL5603988 0.77 TSPO (0.56) MEN1TSHRKMT2ATRPM8ALDH1A1
SCHEMBL741752 0.77 NPSR1 (0.64) MEN1TSHRKMT2ATRPM8ALDH1A1
SCHEMBL27667245 0.76 KMT2A (0.49) MEN1TSHRKMT2AALDH1A1RAB9A
Hydrochloric Acid SCHEMBL8550497 0.74 NPSR1 (0.61) MEN1TSHRKMT2ATRPM8ALDH1A1
SCHEMBL7982563 0.74 ALDH1A1 (0.51) MEN1TSHRKMT2AALDH1A1RAB9A
SCHEMBL7985347 0.74 NPC1 (0.51) MEN1TSHRKMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7324058-A None JP disclosed
EP-0687668-A2 m-Phenylenediamine derivatives and electrophotosensitive material using the same MITA INDUSTRIAL CO., LTD. (JP) 1995-12-20 EP disclosed
JP-H07324058-A M-PHENYLENEDIAMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC SENSITIZER USING THE SAME MITA IND CO LTD 1995-12-12 JP disclosed