Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55533 | 0.87 | HRH1 (0.67) | HRH1KCNH2 | |
| SCHEMBL28021507 | 0.84 | HTT (0.63) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL27711829 | 0.84 | HRH1 (0.48) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL6362147 | 0.82 | KCNH2 (0.83) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL1108959 | 0.81 | ATM (0.66) | HRH1KCNH2ALDH1A1 | |
| SCHEMBL10479209 | 0.81 | HRH1 (0.63) | HRH1KCNH2 | |
| SCHEMBL10568072 | 0.80 | HRH1 (0.62) | HRH1KCNH2 | |
| SCHEMBL9786914 | 0.80 | HRH1 (0.66) | HRH1KCNH2 | |
| SCHEMBL14573191 | 0.80 | KCNH2 (0.58) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL6619451 | 0.78 | HRH1 (0.64) | HRH1KCNH2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004701-B2 | Methods and compositions for treating infection | UNIVERSITY OF ROCHESTER (US) | 2018-06-26 | — | — | US | disclosed |
| EP-1992615-A1 | A process for the preparation of keto compounds | Dipharma Francis S.r.l. (IT) | 2008-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004701-B2 | Methods and compositions for treating infection | MMP8, IFNG, MPO | HRH1 1562/4885KCNH2 1413/4885HTT 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.