Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565446 | 0.75 | GRM6 (0.50) | MAPTGRM6ACHEGAAELANE | |
| SCHEMBL3604990 | 0.73 | MAPT (0.47) | MAPTGRM6MEN1TSHRKMT2A | |
| SCHEMBL12358688 | 0.71 | FUCA1 (0.50) | GBA1MEN1TSHRKMT2AGAA | |
| SCHEMBL19463296 | 0.70 | GAA (0.59) | ACHEMEN1TSHRKMT2AGAA | |
| SCHEMBL19463297 | 0.70 | GAA (0.59) | ACHEMEN1TSHRKMT2AGAA | |
| SCHEMBL4048121 | 0.70 | MAPT (0.68) | MAPTACHE | |
| SCHEMBL6741206 | 0.70 | MAPT (0.68) | MAPTACHE | |
| SCHEMBL27979641 | 0.70 | MAPT (0.68) | MAPTACHE | |
| SCHEMBL14959515 | 0.69 | SIGMAR1 (0.42) | MAPTGRM6GBA1DRD2DRD3 | |
| SCHEMBL14314230 | 0.69 | OPRM1 (0.50) | MAPTACHEMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855452-A | N-substituted azetidine carboxylate derivatives | SHELL OIL COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4778577-A | OXIDATION OF ALCOHOL TO ACID WITH NICKEL/III/COMPOUND | SHELL OIL COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0199413-A2 | Process for preparing azetidine derivatives and novel intermediates therein | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-10-29 | — | — | EP | disclosed |