Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569082 | 0.85 | MT-CO2 (0.47) | ALDH1A1POLBMT-CO2ALOX5MEN1 | |
| SCHEMBL10573727 | 0.85 | ALDH1A1 (0.62) | ALDH1A1POLBGAAHPGDALOX12 | |
| SCHEMBL10572512 | 0.85 | ALDH1A1 (0.62) | ALDH1A1POLBGAAHPGDALOX12 | |
| SCHEMBL10569728 | 0.85 | ALDH1A1 (0.62) | ALDH1A1POLBGAAHPGDALOX12 | |
| SCHEMBL10570458 | 0.84 | MT-CO2 (0.52) | ALDH1A1GAAALOX12MAPTMT-CO2 | |
| SCHEMBL10570992 | 0.84 | POLB (0.58) | ALDH1A1POLBGAAHPGDALOX12 | |
| SCHEMBL10570366 | 0.84 | ALDH1A1 (0.52) | ALDH1A1POLBGAAMAPTMT-CO2 | |
| SCHEMBL10567917 | 0.83 | MT-CO2 (0.63) | ALDH1A1POLBGAAMAPTMT-CO2 | |
| SCHEMBL10569456 | 0.80 | POLB (0.47) | ALDH1A1POLBHPGDMAPTMT-CO2 | |
| SCHEMBL10567104 | 0.80 | SLC6A2 (0.45) | ALDH1A1POLBMT-CO2ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |