Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569492 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPTHSP90AA1HTTKMT2A | |
| SCHEMBL10571688 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTHSP90AA1HTTKMT2A | |
| SCHEMBL10569939 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTHSP90AA1HTTKMT2A | |
| SCHEMBL10569082 | 0.85 | MT-CO2 (0.47) | ALDH1A1KMT2AMEN1POLBMT-CO2 | |
| SCHEMBL10568192 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL10570458 | 0.84 | MT-CO2 (0.52) | ALDH1A1MAPTMT-CO2ALOX5GAA | |
| SCHEMBL10570992 | 0.84 | POLB (0.58) | ALDH1A1MAPTHSP90AA1KMT2AMEN1 | |
| SCHEMBL10567917 | 0.83 | MT-CO2 (0.63) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL10567104 | 0.83 | SLC6A2 (0.45) | ALDH1A1KMT2AMEN1POLBMT-CO2 | |
| SCHEMBL10569934 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTHSP90AA1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |