Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.46 |
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA4 | P22748 | 12/20 | 0.46 |
| ▸ | CA5A | P35218 | 8/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 11/20 | 0.45 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA3 | P07451 | 7/20 | 0.45 |
| ▸ | CA6 | P23280 | 7/20 | 0.45 |
| ▸ | CA7 | P43166 | 7/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA11 | O75493 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563584 | 0.87 | CA12 (0.46) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11559522 | 0.84 | CA1 (0.51) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11751913 | 0.76 | CA2 (0.43) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL18100211 | 0.76 | CA1 (0.72) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL10567054 | 0.76 | RAB9A (0.51) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL10565445 | 0.75 | MAPT (0.47) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11690673 | 0.75 | CA1 (0.43) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11814197 | 0.75 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL999094 | 0.72 | CA2 (0.50) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11704507 | 0.71 | CA1 (0.47) | CA1CA2CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876044-A | PESTICIDES, HERBICIDES | AIR PRODUCTS AND CHEMICALS, INC. | 1989-10-24 | — | — | US | disclosed |
| US-4165229-A | SUBSTITUTED THIADIAZOL-2-YLUREA | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-3972706-A | SUBSTITUTED THIADIAZOL-2-YL-UREAS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |