Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.43 |
| ▸ | CA2 | P00918 | 16/20 | 0.43 |
| ▸ | CA4 | P22748 | 9/20 | 0.42 |
| ▸ | CA5A | P35218 | 5/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 9/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA3 | P07451 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA11 | O75493 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751913 | 0.88 | CA2 (0.43) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL10565445 | 0.84 | MAPT (0.47) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11686381 | 0.83 | CA1 (0.37) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11689676 | 0.82 | TP53 (0.49) | KMT2AMEN1SMN1; SMN2TDP1POLB | |
| SCHEMBL11559522 | 0.80 | CA1 (0.51) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11687601 | 0.79 | SMN1; SMN2 (0.52) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11634995 | 0.78 | POLB (0.51) | KMT2AMEN1SMN1; SMN2TDP1POLB | |
| SCHEMBL11703246 | 0.77 | ALDH1A1 (0.54) | KMT2AMEN1BLMSMN1; SMN2TDP1 | |
| SCHEMBL11669564 | 0.77 | ALDH1A1 (0.51) | KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL11550448 | 0.76 | CA2 (0.40) | CA1CA2CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056383-A | Thiaoiazolyltetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-4053298-A | HERBICIDAL COMPOSITIONS CONTAINING 1-THIADIAZOLYL-6-CARBAMOYLOXYTETRAHYDROPYRIMIDINONES AND METHODS THEREFOR | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4040812-A | Herbicidal carbonates and thiocarbonates of thiadiazolyl-2(1H)-pyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4006009-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3988143-A | 1-Thiadiazolyl-6-alkoxytetrahydropyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979388-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3951976-A | 1-Thiadiazoly-6-carbamoyloxytetrahydropyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
| US-3932410-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |