Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.68 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276991 | 0.83 | KMT2A (0.73) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10568220 | 0.83 | KMT2A (0.73) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL7266954 | 0.81 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10992721 | 0.81 | MEN1 (1.00) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL11133461 | 0.81 | KMT2A (0.72) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL16142173 | 0.80 | ADRA2A (0.69) | KMT2AMEN1IGF1RCYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10990138 | 0.80 | MEN1 (0.97) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL9123119 | 0.80 | MEN1 (0.73) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL4249388 | 0.79 | LMNA (0.60) | KMT2AMEN1OPRM1OPRD1HTR1A | |
| SCHEMBL7287223 | 0.79 | KMT2A (0.62) | KMT2AMEN1OPRM1OPRD1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060163-B1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | KLINGE CO CHEM PHARM FAB (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-6903118-B1 | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides | KLINGE PHARMA GMBH (DE) | 2005-06-07 | — | — | US | disclosed |
| EP-1060163-A1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | Klinge Pharma GmbH (DE) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999031063-A1 | NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |