Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569992 | 0.86 | HTR7 (0.45) | MAPTHTR7MAPK1L3MBTL1DRD2 | |
| SCHEMBL10575372 | 0.86 | DRD2 (0.53) | HTR7DRD2DRD4DRD3 | |
| SCHEMBL10572054 | 0.81 | SCN1A (0.49) | MAPTDRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL10569887 | 0.81 | MAPT (0.41) | MAPTMAPK1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL10571470 | 0.81 | MAPT (0.59) | MAPTHTR7MAPK1L3MBTL1KDM4E | |
| SCHEMBL10571472 | 0.80 | DRD2 (0.61) | MAPTDRD2DRD4DRD3 | |
| SCHEMBL10572593 | 0.77 | HTR7 (0.44) | MAPTHTR7MAPK1L3MBTL1DRD2 | |
| SCHEMBL10666646 | 0.77 | HTR7 (0.44) | MAPTHTR7MAPK1L3MBTL1DRD2 | |
| SCHEMBL10570061 | 0.75 | HTR7 (0.44) | MAPTHTR7MAPK1L3MBTL1DRD2 | |
| SCHEMBL10572146 | 0.74 | DRD2 (0.62) | HTR7DRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |