Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570061 | 0.90 | HTR7 (0.44) | HTR7MAPTDRD2DRD4DRD3 | |
| SCHEMBL10572344 | 0.87 | HTR7 (0.42) | HTR7MAPTDRD2DRD4DRD3 | |
| SCHEMBL10575372 | 0.85 | DRD2 (0.53) | HTR7DRD2DRD4DRD3 | |
| SCHEMBL10571746 | 0.80 | HTR7 (0.66) | HTR7MAPTLMNAMAPK1L3MBTL1 | |
| SCHEMBL10568883 | 0.79 | HTR7 (0.51) | HTR7MAPTDRD2DRD4DRD3 | |
| SCHEMBL10571472 | 0.79 | DRD2 (0.61) | MAPTDRD2DRD4DRD3LMNA | |
| SCHEMBL10569921 | 0.78 | HTR7 (0.47) | HTR7MAPTDRD2DRD4DRD3 | |
| SCHEMBL10568253 | 0.77 | MAPT (0.42) | HTR7SMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL10568544 | 0.76 | HTR7 (0.49) | HTR7MAPTDRD2DRD4DRD3 | |
| SCHEMBL10572054 | 0.75 | SCN1A (0.49) | SMN1; SMN2MAPTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |