Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568273 | 1.00 | HCAR2 (0.48) | HCAR2DAOMMP9NPC1ALDH1A1 | |
| SCHEMBL5677189 | 0.70 | LMNA (0.59) | HCAR2NPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9270808 | 0.68 | NPC1 (0.43) | HCAR2MMP9NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9270809 | 0.68 | NPC1 (0.43) | HCAR2MMP9NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23174842 | 0.67 | ALDH1A1 (0.39) | HCAR2MMP9ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1124646 | 0.67 | SMN1; SMN2 (0.44) | NPC1ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL1902161 | 0.67 | KDM4E (0.41) | HCAR2NPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6181311 | 0.67 | KDM4E (0.41) | HCAR2NPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25177052 | 0.67 | ALDH1A1 (0.45) | HCAR2MMP9NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1124648 | 0.67 | SMN1; SMN2 (0.44) | NPC1ALDH1A1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835280-A | Indoline compounds for synthesis of pharmaceutically active pyrrolobenzimidazoles | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-30 | — | — | US | disclosed |