Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4304157 | 0.73 | KDM4E (0.43) | LMNAKDM4EHPGDSMN1; SMN2POLB | |
| SCHEMBL9453125 | 0.73 | KDM4E (0.43) | LMNAKDM4EHPGDSMN1; SMN2POLB | |
| SCHEMBL1757968 | 0.71 | — | — | |
| SCHEMBL10568277 | 0.70 | HCAR2 (0.48) | LMNAKDM4EHPGDNPC1SMN1; SMN2 | |
| SCHEMBL10568273 | 0.70 | HCAR2 (0.48) | LMNAKDM4EHPGDNPC1SMN1; SMN2 | |
| SCHEMBL10725655 | 0.69 | LMNA (0.67) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL11129796 | 0.69 | LMNA (0.67) | LMNAKDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL11660064 | 0.65 | P4HTM (0.68) | LMNAKDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11660063 | 0.65 | P4HTM (0.68) | LMNAKDM4EHPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11330726 | 0.64 | KMT2A (0.56) | CYP1A2NPC1RAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988045-B1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2006-02-08 | — | — | EP | disclosed |