SCHEMBL1056828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20197285	0.88	GSK3A (0.42)	ADORA3ADORA1ADORA2AGSK3AGSK3B
	SCHEMBL4370028	0.82	ADORA1 (0.41)	ADORA3ADORA1ADORA2ADDAH1GSK3A
	SCHEMBL4371769	0.81	GAA (0.41)	ADORA3ADORA1ADORA2ADDAH1GSK3A
	SCHEMBL1080357	0.78	CCNB2 (0.40)	GSK3AGSK3BCDK1CDK5CCNB2
	SCHEMBL24422924	0.78	ADORA3 (0.38)	ADORA3ADORA1ADORA2ADDAH1GSK3A
	SCHEMBL1058944	0.76	CCNB2 (0.38)	ADORA3GSK3AGSK3BCDK1CDK5
	SCHEMBL15925247	0.74	DAO (0.39)	AURKAAURKBPDE3BPDE3A
	SCHEMBL4295424	0.73	NOS2 (0.58)	GSK3AGSK3BCDK1CDK5CDK2
	SCHEMBL4370037	0.72	NOS2 (0.41)	GSK3AGSK3BCDK1CDK5MAPK8
	SCHEMBL32671116	0.72	MAPK14 (0.35)	GSK3AGSK3BCDK1CDK5CCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.