SCHEMBL10568453

SCHEMBL10568453

Nc1cc2cc(-n3nc4c(c3Cl)CCCC4)c(F)cc2s1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.32
BCHE P06276 4/20 0.32
GRIN1 Q05586 3/20 0.32
GRIN2A Q12879 3/20 0.32
CHRM1 P11229 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9368563 0.84 DRD2 (0.39) ACHEBCHEGRIN1GRIN2A
SCHEMBL10742487 0.80 ACHE (0.35) ACHEBCHEGRIN1GRIN2ACHRM1
SCHEMBL9369802 0.76 MAPT (0.41) ACHEBCHEGRIN1GRIN2ACHRM1
SCHEMBL9368678 0.76 CMA1 (0.35)
SCHEMBL9369024 0.76 PPOX (0.34)
SCHEMBL9368864 0.75 CNR2 (0.33)
SCHEMBL7797875 0.74
SCHEMBL9835068 0.73 ACHE (0.40) ACHEBCHEGRIN1GRIN2A
SCHEMBL7941439 0.73 ACHE (0.38) ACHEBCHEGRIN1GRIN2ACHRM1
SCHEMBL11081553 0.72 SMN1; SMN2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4831150-A HERBICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-16 US disclosed