Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84842 | 0.74 | MAPT (0.50) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL24194048 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL12604459 | 0.70 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL3350602 | 0.68 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL10571882 | 0.67 | TSHR (0.42) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL18748029 | 0.66 | TDP1 (0.41) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL11978686 | 0.64 | KMT2A (0.47) | MAPTHPGDKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL18281469 | 0.63 | LMNA (0.94) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL12307044 | 0.62 | SMN1; SMN2 (0.54) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL10780626 | 0.62 | SRD5A1 (0.41) | ALDH1A1LMNAKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810711-A | ANXIOLYTIC, ANTICONVULSANT, ANTIULCER | SYNTHELABO (FR) | 1989-03-07 | — | — | US | disclosed |