SCHEMBL3350602

SCHEMBL3350602

Cc1ccc(-c2cn(-c3ccccc3C)c(S)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.47
NPC1 O15118 9/20 0.47
RAB9A P51151 9/20 0.47
GAA P10253 3/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
ALDH1A3 P47895 2/20 0.43
SLC2A1 P11166 1/20 0.43
KDM4E B2RXH2 9/20 0.41
SMN1; SMN2 Q16637 6/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
MITF O75030 2/20 0.41
KDM5A P29375 1/20 0.41
KDM5C P41229 1/20 0.41
PAX8 Q06710 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
USP2 O75604 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL10012418 0.74 SMN1; SMN2 (0.46) ALDH1A1NPC1RAB9AGAANFKB1
SCHEMBL5318961 0.72 ALDH1A1 (0.53) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
Bromide SCHEMBL10012835 0.70 RAB9A (0.50) NPC1RAB9AGAAALDH1A3KDM4E
SCHEMBL28147063 0.69 FLT3 (0.63) ALDH1A1NPC1RAB9AGAANFKB1
SCHEMBL5126771 0.68 RAB9A (0.44) ALDH1A1NPC1RAB9AGAAALDH1A3
SCHEMBL10568498 0.68 ALDH1A1 (0.46) ALDH1A1NPC1RAB9AGAANFKB1
SCHEMBL8699160 0.64 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2L3MBTL1MAPTHPGD
SCHEMBL2617338 0.64 ALDH1A1 (1.00) ALDH1A1NPC1RAB9AGAANFKB1
P-Xylene SCHEMBL28832777 0.63 ACHE (0.67) ALDH1A1NPC1RAB9ANFKB1NFKB2
SCHEMBL4549458 0.63 ALDH1A3 (0.51) NPC1RAB9AGAAALDH1A3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP disclosed
CN-101909769-B Self assembled molecules on immersion silver coatings ENTHONE 2014-07-02 CN disclosed
US-8741390-B2 Metallic surface enhancement ENTHONE INC. (US) 2014-06-03 US disclosed
CN-101743210-B Metallic surface enhancement ENTHONE 2013-04-17 CN disclosed
US-8323741-B2 Self assembled molecules on immersion silver coatings CITIBANK, N.A. 2012-12-04 US disclosed
US-20120276409-A1 SELF ASSEMBLED MOLECULES ON IMMERSION SILVER COATINGS ENTHONE INC. (US) 2012-11-01 US disclosed
US-8216645-B2 Self assembled molecules on immersion silver coatings ENTHONE INC. (US) 2012-07-10 US disclosed
CN-101909769-A Self assembled molecules on immersion silver coatings ENTHONE 2010-12-08 CN disclosed
US-20100151263-A1 METALLIC SURFACE ENHANCEMENT ENTHONE INC. (US) 2010-06-17 US disclosed
CN-101743210-A Metal surface enhanced ENTHONE 2010-06-16 CN disclosed
EP-2142485-A1 METALLIC SURFACE ENHANCEMENT Enthone, Inc. (US) 2010-01-13 EP disclosed
US-20090121192-A1 SELF ASSEMBLED MOLECULES ON IMMERSION SILVER COATINGS ENTHONE INC. (US) 2009-05-14 US disclosed
WO-2008131206-A1 METALLIC SURFACE ENHANCEMENT ENTHONE INC. (US) 2008-10-30 WO disclosed