Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050809 | 0.82 | PTGS2 (0.57) | PTGS1PTGS2LMNA | |
| SCHEMBL6050648 | 0.82 | PTGS2 (0.77) | PTGS1PTGS2 | |
| SCHEMBL8437240 | 0.82 | ALDH1A1 (0.41) | PTGS1PTGS2ALDH1A1MAPK1CYP2A6 | |
| SCHEMBL16266879 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPK1CYP2A6CYP2B6DAPK3 | |
| SCHEMBL2286545 | 0.78 | CYP2A6 (0.38) | ALDH1A1MAPK1CYP2A6CYP2B6DAPK3 | |
| SCHEMBL12912902 | 0.76 | CYP2A6 (0.43) | ALDH1A1MAPK1CYP2A6CYP2B6DAPK3 | |
| SCHEMBL6036925 | 0.76 | BACE1 (0.41) | PTGS2ALDH1A1CYP2A6CYP2B6DAPK3 | |
| SCHEMBL11678420 | 0.74 | CYP2A6 (0.38) | ALDH1A1MAPK1CYP2A6CYP2B6DAPK3 | |
| SCHEMBL27836567 | 0.74 | CYP2A6 (0.47) | ALDH1A1CYP2A6CYP2B6DAPK3PRKD3 | |
| Phosphine SCHEMBL28718427 | 0.74 | BACE1 (0.41) | PTGS2ALDH1A1CYP2A6CYP2B6DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041376-A | A kind of annular metal iridium complex and its preparation method and application | 江西师范大学 | 2019-07-23 | — | — | CN | claimed |
| CN-110016335-A | A kind of pure organic room temperature phosphorimetry material and its preparation method and application with ehter bond | 广东工业大学 | 2019-07-16 | — | — | CN | claimed |
| CN-109053740-A | A kind of H-type acceptor material and preparation method thereof | 南京邮电大学 | 2018-12-21 | — | — | CN | claimed |
| CN-106960912-B | Organic illuminating element, organic light-emitting display device and its compound | 德山新勒克斯有限公司 | 2019-12-03 | — | — | CN | disclosed |
| CN-110498765-A | Compound, electroluminescent organic material and organic electroluminescence device | BEIJING ETERNAL MAT TECH CO LTD | 2019-11-26 | — | — | CN | disclosed |
| CN-106699634-B | A kind of aromatic amine derivant and its preparation method and application | 长春海谱润斯科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-110105225-A | A kind of electroluminescent organic material and the organic electroluminescence device comprising the material | 陕西莱特光电材料股份有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-107075360-B | Organic photovoltaic component and display device | 三星SDI株式会社 | 2019-08-02 | — | — | CN | disclosed |
| CN-110041376-A | A kind of annular metal iridium complex and its preparation method and application | 江西师范大学 | 2019-07-23 | — | — | CN | disclosed |
| CN-110016335-A | A kind of pure organic room temperature phosphorimetry material and its preparation method and application with ehter bond | 广东工业大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-108864416-B | Polymer luminescent material and its preparation method and application | 北京化工大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-108003121-A | A kind of phenanthrene class compound and application thereof and organic electroluminescence device | 上海道亦化工科技有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-103080105-A | Nitrogen-bonded 5-membered heterocyclic substituted dibenzofurans and dibenzothiophenes and their use in organic electronics | BASF SE | 2013-05-01 | — | — | CN | disclosed |
| CN-1706839-B | Material containing non-benzenoid aryl spiro and its synthesis and application | UNIV FUDAN | 2010-05-05 | — | — | CN | disclosed |
| CN-1749254-A | Double spiro material containing heteroaton and its synthetic method and use | UNIV FUDAN (CN) | 2006-03-22 | — | — | CN | disclosed |
| CN-1706839-A | Non-benzenoid aryl spiro material and its synthesis and application | UNIV FUDAN (CN) | 2005-12-14 | — | — | CN | disclosed |
| US-4820827-A | 2,3-diaryl-5-bromothiophene compounds of use for the treatment of inflammaton and dysmenorrhea | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4590205-A | Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0087629-B1 | ANTIINFLAMMATORY AND/OR ANALGESIC 2,3-DIARYL-5-HALO THIOPHENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |
| EP-0087629-A2 | Antiinflammatory and/or analgesic 2,3-Diaryl-5-halo thiophenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-09-07 | — | — | EP | disclosed |