SCHEMBL2286545

SCHEMBL2286545

Sc1scc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.38
CYP2B6 P20813 1/20 0.38
DAPK3 O43293 1/20 0.36
PRKD3 O94806 1/20 0.36
MAP4K4 O95819 1/20 0.36
ABL1 P00519 1/20 0.36
NTRK1 P04629 1/20 0.36
LCK P06239 1/20 0.36
CSF1R P07333 1/20 0.36
RET P07949 1/20 0.36
MET P08581 1/20 0.36
PDGFRB P09619 1/20 0.36
FGFR1 P11362 1/20 0.36
PDGFRA P16234 1/20 0.36
PRKACA P17612 1/20 0.36
FLT1 P17948 1/20 0.36
LTK P29376 1/20 0.36
KDR P35968 1/20 0.36
MAP2K2 P36507 1/20 0.36
MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29217102 0.78 DAPK3 (0.43) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL10568574 0.78 PTGS1 (0.49) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL6036925 0.76 BACE1 (0.41) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL12912902 0.76 CYP2A6 (0.43) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL8219401 0.74 ALDH1A1 (0.49) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL11678420 0.74 CYP2A6 (0.38) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
Phosphine SCHEMBL28718427 0.74 BACE1 (0.41) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL27836567 0.74 CYP2A6 (0.47) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL12912881 0.72 ALDH1A1 (0.37) CYP2A6CYP2B6DAPK3PRKD3MAP4K4
SCHEMBL12912904 0.72 ALDH1A1 (0.37) CYP2A6CYP2B6DAPK3PRKD3MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696216-B2 A PHOTO ACID GENERATOR USED IN GENERATING AN ACID FOR CHEMICALLY CLEAVING ACID SENSITIVE SIDE CHAINS OF A CHEMICALLY AMPLIFIED BASE POLYMER CONTAINS A SULFONIUM OR IODONIUM SALT CONTAINING ATLEAST ONE THIOPHENE RING INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-02-24 US claimed
US-20030008230-A1 Thiophene-containing photo acid generators for photolithography INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-01-09 US claimed
WO-2003003120-A1 THIOPHENE-CONTAINING PHOTO ACID GENERATORS FOR PHOTOLITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2003-01-09 WO claimed
US-11339231-B2 Olefin-based resin composition, manufacturing method therefor, and molded article thereof ADEKA CORPORATION (JP) 2022-05-24 US disclosed
US-20200317830-A1 OLEFIN-BASED RESIN COMPOSITION, MANUFACTURING METHOD THEREFOR, AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2020-10-08 US disclosed
CN-109863156-A Novel compound, composition using same, olefin resin composition, molded article thereof, and method for improving impact resistance of molded article 株式会社ADEKA 2019-06-07 CN disclosed
US-9535325-B2 Onium salt, chemically amplified positive resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-01-03 US disclosed
CN-103781813-B The epoxy resin adduct mixed 蓝立方知识产权有限责任公司 2016-09-14 CN disclosed
US-9329476-B2 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-03 US disclosed
US-20150198876-A1 ONIUM SALT, CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-16 US disclosed
US-20150198877-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-16 US disclosed
US-8795942-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-05 US disclosed
US-8283104-B2 Sulfonate and its derivative, photosensitive acid generator, and resist composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-08-04 US disclosed
US-20100209827-A1 NOVEL SULFONATE AND ITS DERIVATIVE, PHOTOSENSITIVE ACID GENERATOR, AND RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-19 US disclosed
US-20080153030-A1 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-06-26 US disclosed
US-6696216-B2 A PHOTO ACID GENERATOR USED IN GENERATING AN ACID FOR CHEMICALLY CLEAVING ACID SENSITIVE SIDE CHAINS OF A CHEMICALLY AMPLIFIED BASE POLYMER CONTAINS A SULFONIUM OR IODONIUM SALT CONTAINING ATLEAST ONE THIOPHENE RING INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-02-24 US disclosed
US-20030008230-A1 Thiophene-containing photo acid generators for photolithography INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-01-09 US disclosed
WO-2003003120-A1 THIOPHENE-CONTAINING PHOTO ACID GENERATORS FOR PHOTOLITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2003-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS RPS4Y1, ETV6, RPS4X CYP2A6 4058/4885CYP2B6 3846/4885DAPK3 4507/4885
US-20100209827-A1 NOVEL SULFONATE AND ITS DERIVATIVE, PHOTOSENSITIVE ACID GENERATOR, AND RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME DAP3, MRPS23, ASIC3 CYP2A6 2299/4885CYP2B6 2015/4885DAPK3 729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.