Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571746 | 0.89 | HTR7 (0.66) | HTR7MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL10568734 | 0.88 | MEN1 (0.48) | L3MBTL1KMT2A | |
| SCHEMBL10568516 | 0.87 | HTR7 (0.50) | HTR7MAPTALDH1A1LMNA | |
| SCHEMBL10660200 | 0.85 | HTR7 (0.48) | HTR7MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL10570860 | 0.84 | DRD2 (0.61) | HTR7DRD2ADRB2CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL10572084 | 0.83 | DRD2 (0.60) | HTR7DRD2ADRB2CHRM2CHRM4 | |
| SCHEMBL10572344 | 0.81 | HTR7 (0.42) | HTR7MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL10571106 | 0.80 | DRD2 (0.68) | DRD2DRD4DRD3 | |
| SCHEMBL10665459 | 0.80 | HRH1 (0.59) | HTR7DRD2ADRB2CHRM2CHRM4 | |
| SCHEMBL10666646 | 0.79 | HTR7 (0.44) | HTR7MAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |