Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10898517 | 0.99 | LMNA (0.57) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL24673257 | 0.99 | LMNA (0.57) | LMNAMAPK1MAPTRAB9ATSHR | |
| Bromide SCHEMBL29942515 | 0.97 | LMNA (0.56) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL10397560 | 0.87 | RAB9A (0.62) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL10900943 | 0.86 | KCNH2 (0.66) | LMNARAB9ASMN1; SMN2NPC1TNF | |
| SCHEMBL345054 | 0.85 | TSHR (0.60) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL3569140 | 0.85 | CHKA (0.60) | MAPK1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7499633 | 0.85 | RAB9A (0.60) | LMNAMAPK1MAPTRAB9ATSHR | |
| Hydrochloric Acid SCHEMBL10901510 | 0.85 | KCNH2 (0.65) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL347958 | 0.84 | CHKA (0.62) | LMNAMAPK1MAPTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |
| US-4826974-A | REARRANGEMENT OF SPIRO COMPOUND | RHONE-POULENC SANTE (FR) | 1989-05-02 | — | — | US | disclosed |
| US-4769366-A | Novel 1,3-disubstituted pyrrolo[1,2-a]azepinone derivatives having anti-psychotic activity and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-09-06 | — | — | US | disclosed |