Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29942515 | 0.99 | LMNA (0.56) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL10568920 | 0.99 | LMNA (0.58) | LMNAMAPK1MAPTRAB9ATSHR | |
| Hydrochloric Acid SCHEMBL10898517 | 0.97 | LMNA (0.57) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL5038790 | 0.86 | CHKA (0.59) | MAPK1MAPTSMN1; SMN2KDM4ECXCR4 | |
| SCHEMBL10397560 | 0.85 | RAB9A (0.62) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL10900943 | 0.85 | KCNH2 (0.66) | LMNARAB9ASMN1; SMN2HRH3NPC1 | |
| SCHEMBL345054 | 0.84 | TSHR (0.60) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL7499633 | 0.84 | RAB9A (0.60) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL3569140 | 0.84 | CHKA (0.60) | MAPK1MAPTSMN1; SMN2KDM4ECXCR4 | |
| Hydrochloric Acid SCHEMBL10901510 | 0.84 | KCNH2 (0.65) | LMNAMAPK1MAPTRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204065-A1 | IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |