Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507569 | 0.94 | TOP2A (0.51) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10508242 | 0.92 | ALDH1A1 (0.59) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10507545 | 0.88 | ALDH1A1 (0.46) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10569538 | 0.85 | KCNH2 (0.69) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8557025 | 0.85 | MEN1 (0.49) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10575167 | 0.84 | KCNH2 (0.62) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10510579 | 0.84 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10507575 | 0.84 | LMNA (0.45) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10508029 | 0.84 | ALDH1A1 (0.59) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10572243 | 0.83 | KCNH2 (0.60) | KCNH2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880806-A | BACTERICIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-11-14 | — | — | US | claimed |
| US-4880806-A | BACTERICIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-11-14 | — | — | US | disclosed |