Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565487 | 0.83 | SORD (0.42) | GPR119SORDGRM1AR | |
| Hydrochloric Acid SCHEMBL27675360 | 0.82 | SORD (0.35) | GPR119SORDGRM1PDCD1LG2CD274 | |
| SCHEMBL27693764 | 0.77 | ROCK2 (0.48) | CHRNB4CHRNA3ROCK2 | |
| SCHEMBL26972646 | 0.75 | GRM1 (0.40) | GPR119SORDGRM1ROCK2PRKG1 | |
| SCHEMBL30803917 | 0.73 | PIM1 (0.42) | GPR119SORDGRM1MAP4K4 | |
| SCHEMBL10569035 | 0.72 | MAP4K4 (0.46) | GPR119SORDGRM1PDCD1LG2CD274 | |
| SCHEMBL31087030 | 0.71 | CYP2D6 (0.48) | — | |
| SCHEMBL10332985 | 0.66 | LRRK2 (0.48) | GPR119SORDGRM1 | |
| SCHEMBL31087011 | 0.65 | GPR119 (0.36) | GPR119SORDGRM1ROCK2PRKG1 | |
| SCHEMBL13703139 | 0.65 | GPR119 (0.52) | GPR119SORDGRM1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820708-A | ANTISECRETORY AGENTS; GASTROINTESTINAL DISORDERS | SMITH KLINE & FRENCH LABORATORIES (GB) | 1989-04-11 | — | — | US | disclosed |
| US-4777172-A | ANTIGASTRIC ACID SECRETORY AGENT | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-10-11 | — | — | US | disclosed |
| CN-86102398-A | The preparation method of substituted benzimidazole derivative | — | 1986-11-12 | — | — | CN | disclosed |
| EP-0198583-A1 | Heterocyclic compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-10-22 | — | — | EP | disclosed |