Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052532 | 0.92 | LMNA (0.61) | LMNAGAAKDM4EJAK2GMNN | |
| Hydrochloric Acid SCHEMBL11050094 | 0.91 | LMNA (0.60) | LMNAGAAKDM4EJAK2GMNN | |
| SCHEMBL10570535 | 0.83 | MEN1 (0.69) | LMNAGAAKDM4EJAK2GMNN | |
| SCHEMBL10567039 | 0.82 | ALDH1A1 (0.75) | LMNAGAAKDM4EJAK2GMNN | |
| SCHEMBL10566363 | 0.81 | MTOR (0.60) | LMNAGAAKDM4EJAK2GMNN | |
| SCHEMBL10564641 | 0.81 | PIK3CG (0.71) | LMNAGAAKDM4EJAK2GMNN | |
| SCHEMBL10566936 | 0.81 | MTOR (0.60) | LMNAGAAKDM4EJAK2GMNN | |
| SCHEMBL10483775 | 0.81 | MTOR (0.60) | LMNAGAAKDM4EJAK2GMNN | |
| 2-Pyrrolidone SCHEMBL11073758 | 0.79 | ALDH1A1 (0.46) | LMNAGAAKDM4EJAK2GMNN | |
| Dimethylamine SCHEMBL10566645 | 0.79 | ALDH1A1 (0.69) | LMNAGAAKDM4EJAK2GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874763-A | ANTIARRHYTHMIA AGENTS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 1989-10-17 | — | — | US | claimed |
| US-4874763-A | ANTIARRHYTHMIA AGENTS | ROEHM GMBH CHEMISCHE FABRIK (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0318795-A2 | Pharmaceutically active pteridin derivatives | Röhm GmbH (DE) | 1989-06-07 | — | — | EP | disclosed |