Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052532 | 0.85 | LMNA (0.61) | ALDH1A1GAALMNAPKMMAPK1 | |
| 2-Pyrrolidone SCHEMBL11067547 | 0.85 | PIK3CG (0.59) | ALDH1A1GAALMNAPKMMAPK1 | |
| Hydrochloric Acid SCHEMBL11050094 | 0.84 | LMNA (0.60) | ALDH1A1GAALMNAPKMMAPK1 | |
| SCHEMBL10569845 | 0.79 | LMNA (0.53) | ALDH1A1GAALMNAPKMMAPK1 | |
| Nitrobenzene SCHEMBL10419563 | 0.67 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPK1CYP1A2HPGD | |
| SCHEMBL10569177 | 0.67 | MTOR (0.63) | ALDH1A1GAALMNAPKMMAPK1 | |
| SCHEMBL10537075 | 0.66 | PIK3CG (0.84) | ALDH1A1GAALMNAPKMMAPK1 | |
| SCHEMBL11052797 | 0.66 | MTOR (0.71) | ALDH1A1GAALMNAPKMMAPK1 | |
| SCHEMBL10456499 | 0.66 | MTOR (0.71) | ALDH1A1GAALMNAPKMMAPK1 | |
| Triamterene SCHEMBL40707 | 0.66 | ALDH1A1 (1.00) | ALDH1A1GAALMNAPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425346-A | ANTIGLAUCOMA AGENTS | SMITH AND NEPHEW ASSOCIATED COMPANIES LIMITED (GB) | 1984-01-10 | — | — | US | disclosed |