Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.94 |
| ▸ | DRD4 | P21917 | 6/20 | 0.76 |
| ▸ | DRD3 | P35462 | 6/20 | 0.76 |
| ▸ | MAOA | P21397 | 3/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | MLNR | O43193 | 1/20 | 0.69 |
| ▸ | HTR3B | O95264 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097745 | 0.93 | DRD2 (0.82) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL10571409 | 0.89 | DRD2 (0.94) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL2615543 | 0.88 | DRD2 (0.83) | DRD2DRD4DRD3MAOAHTR3E | |
| SCHEMBL10570451 | 0.87 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL13532795 | 0.86 | DRD2 (1.00) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL23097579 | 0.86 | DRD2 (0.71) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL10571607 | 0.86 | DRD2 (0.94) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL10573201 | 0.86 | DRD2 (0.95) | DRD2DRD4DRD3 | |
| SCHEMBL3258529 | 0.85 | DRD2 (0.81) | DRD2DRD4DRD3MAOAHTR3E | |
| Hydrochloric Acid SCHEMBL10572620 | 0.85 | DRD2 (0.92) | DRD2DRD4DRD3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | claimed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |