Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.71 |
| ▸ | DRD4 | P21917 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097745 | 0.91 | DRD2 (0.82) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097589 | 0.89 | DRD2 (0.71) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097560 | 0.88 | DRD2 (0.71) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL10572858 | 0.86 | DRD2 (0.94) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097764 | 0.86 | DRD2 (0.72) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL10489982 | 0.85 | DRD2 (0.69) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097687 | 0.84 | KCNH2 (0.54) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097632 | 0.83 | MAOB (0.64) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097721 | 0.83 | DRD2 (0.56) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL23097565 | 0.82 | DRD2 (0.63) | DRD2DRD4DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170334-B1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | UNIV EMORY (US) | 2021-03-17 | — | — | EP | disclosed |