Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31714994 | 0.77 | TSHR (0.57) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL13077554 | 0.76 | TSHR (0.63) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL3735853 | 0.76 | TSHR (0.63) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL3735855 | 0.76 | TSHR (0.63) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL10573558 | 0.73 | KMT2A (0.38) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL31714667 | 0.69 | TSHR (0.39) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL6969092 | 0.69 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL13775361 | 0.69 | GSK3B (0.41) | KMT2ATSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16424936 | 0.68 | TSHR (0.49) | KMT2ATSHRTDP1ALDH1A1MAPT | |
| SCHEMBL9765459 | 0.68 | MEN1 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-4880933-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | disclosed |