Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735853 | 0.96 | TSHR (0.63) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL13077554 | 0.96 | TSHR (0.63) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL3735855 | 0.96 | TSHR (0.63) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL31714667 | 0.80 | TSHR (0.39) | TSHRALDH1A1MAPTTDP1LMNA | |
| SCHEMBL10573552 | 0.77 | KMT2A (0.36) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL13041020 | 0.77 | TSHR (0.71) | TSHRALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8519307 | 0.75 | TSHR (0.53) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL668453 | 0.74 | TSHR (0.56) | TSHRALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8300576 | 0.73 | INMT (0.56) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL6121644 | 0.71 | TSHR (0.59) | TSHRALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2025-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | TSHR 4788/4885ALDH1A1 3515/4885MAPT 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.