Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.30 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573577 | 1.00 | NAAA (0.48) | NAAAFAAHCHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL10576528 | 0.82 | CHRNB2 (0.34) | NAAAFAAHCHRNB2CHRNA4HSD17B10 | |
| SCHEMBL10576525 | 0.82 | CHRNB2 (0.34) | NAAAFAAHCHRNB2CHRNA4HSD17B10 | |
| SCHEMBL10575505 | 0.82 | CHRNB2 (0.33) | NAAAFAAHCHRNB2CHRNA4 | |
| SCHEMBL10575764 | 0.80 | KMT2A (0.39) | NAAAFAAHCHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL10575773 | 0.80 | KMT2A (0.39) | NAAAFAAHCHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7995353 | 0.80 | ALDH1A1 (0.36) | NAAAFAAHCHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7995355 | 0.80 | ALDH1A1 (0.36) | NAAAFAAHCHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL10573990 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNA4ALDH1A1MAPT | |
| SCHEMBL11370007 | 0.74 | NAAA (0.77) | NAAAFAAHCHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-4880933-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | disclosed |