SCHEMBL105740

SCHEMBL105740

CC(C)(C)c1ccc(-c2[c]ccc(-c3cc[c]c(-c4ccc(C(C)(C)C)cc4C(C)(C)C)c3-c3ccc(C(C)(C)C)cc3C(C)(C)C)c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1242637 0.90 ALDH1A1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL18059798 0.89 ALDH1A1 (0.30) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1898775 0.89 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1902139 0.86 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL1537930 0.86 ALDH1A1 (0.36) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL17968640 0.75 GHSR (0.30)
SCHEMBL2111870 0.74
SCHEMBL29763177 0.74 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL2357462 0.74 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29388693 0.74 ALDH1A1 (0.47) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2878628-B1 Polyester compounds LANXESS DEUTSCHLAND GMBH (DE) 2017-01-11 EP claimed
EP-2285865-B1 ALKYL PHENOL FOR ADJUSTING THE MOLECULAR WEIGHT AND COPOLYCARBONATE HAVING IMPROVED PROPERTIES BAYER IP GMBH (DE) 2015-06-24 EP claimed
US-20150148466-A1 POLYESTER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2015-05-28 US claimed
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US claimed
EP-2285905-B1 IMPACT-MODIFIED POLYCARBONATE COMPOSITIONS HAVING HIGH HYDROLYSIS RESISTANCE AND A LIGHT NATURAL COLOUR BAYER MATERIALSCIENCE AG (DE) 2012-07-25 EP claimed
US-12043724-B2 Curable composition, film, laminated body, and display apparatus SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
EP-3916051-B1 ASA-BASED RESIN COMPOSITION, MOLDED PRODUCT COMPRISING SAME, AND METHOD FOR MANUFACTURING MOLDED PRODUCT LG CHEMICAL LTD (KR) 2024-06-26 EP disclosed
US-12007093-B2 Three part headlamp assembly COVESTRO LLC (US) 2024-06-11 US disclosed
US-11970556-B2 Methacrylic resin, method of manufacturing methacrylic resin, methacrylic resin composition, shaped article, optical components, and automotive part ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-04-30 US disclosed
US-20240101895-A1 METHOD FOR PRODUCING PHOSPHOR AND PHOSPHOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-03-28 US disclosed
US-20240052158-A1 POLYCARBONATE POLYESTER COMPOSITION, MOLDING COMPOUND AND MOLDING BODY HAVING A GOOD IMPACT STRENGTH AND HIGH THERMAL LOADING CAPABILITY COVESTRO DEUTSCHLAND AG (DE) 2024-02-15 US disclosed
EP-4289791-A1 PHOSPHOR AND METHOD FOR PRODUCING PHOSPHOR Sumitomo Chemical Company Limited (JP) 2023-12-13 EP disclosed
US-7160587-B2 Plastic substrate for display and display element TOSOH CORPORATION (JP) 2007-01-09 US disclosed
EP-1712586-A1 Flame-retarded foamed plastic compositions and shaped articles Dai-Ichi F R Co., Ltd. (JP) 2006-10-18 EP disclosed
US-20060229372-A1 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2006-10-12 US disclosed
US-20060219294-A1 Oxide semiconductor electrode, dye-sensitized solar cell, and, method of producing the same DAI NIPPON PRINTING CO., LTD. 2006-10-05 US disclosed
US-20060201544-A1 Filler sheet for solar cell module, and solar cell module using the same DAI NIPPON PRINTING CO., LTD. (JP) 2006-09-14 US disclosed
US-20060142490-A1 Filler layer for solar cell module and solar cell module using same DAI NIPPON PRINTING CO., LTD. (JP) 2006-06-29 US disclosed
US-20050121817-A1 Process for mixing polymer melts with additives BAYER MATERIALSCIENCE AG (DE) 2005-06-09 US disclosed
US-20050059777-A1 Plastic substrate for display and display element TOSOH CORPORATION (JP) 2005-03-17 US disclosed