Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 5/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578757 | 0.89 | KDM4E (0.50) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10579000 | 0.78 | CYP2C9 (0.43) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10576187 | 0.78 | NPBWR1 (0.46) | KDM4EALDH1A1HPGDHSD17B10HDAC6 | |
| SCHEMBL10578398 | 0.76 | SCD (0.48) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10574973 | 0.75 | PKN1 (0.52) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10579076 | 0.75 | KDM4E (0.47) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL25110163 | 0.75 | HDAC6 (0.57) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10575366 | 0.74 | PKN1 (0.53) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10578748 | 0.74 | KDM4E (0.51) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL10576368 | 0.74 | PKN1 (0.48) | PKN1PKN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |