Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578159 | 0.88 | KDM4E (0.47) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10574269 | 0.83 | NPC1 (0.48) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10575145 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10578101 | 0.81 | TRPV1 (0.46) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10573902 | 0.80 | NPC1 (0.54) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10578169 | 0.80 | SLC2A1 (0.51) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10572942 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10574944 | 0.79 | CHEK2 (0.56) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10576972 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4ENPC1ALDH1A1PKM | |
| SCHEMBL10576178 | 0.79 | NPBWR1 (0.46) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |