Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574279 | 0.92 | SLC2A1 (0.55) | NPC1SMN1; SMN2RAB9AALDH1A1PKM | |
| SCHEMBL10580688 | 0.89 | HDAC6 (0.52) | SMN1; SMN2TRPV1MAPTNPBWR1TP53 | |
| SCHEMBL10574665 | 0.88 | NPBWR1 (0.47) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL10576075 | 0.88 | ALOX5 (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10577985 | 0.87 | NPBWR1 (0.46) | RAB9ATRPV1NPBWR1CHEK2HDAC6 | |
| SCHEMBL10578691 | 0.87 | GUSB (0.43) | NPC1SMN1; SMN2RAB9AALDH1A1PKM | |
| SCHEMBL10577324 | 0.87 | DGAT1 (0.46) | SMN1; SMN2TRPV1MAPTNPBWR1CHEK2 | |
| SCHEMBL10578441 | 0.87 | HDAC6 (0.46) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL10574083 | 0.86 | LOXL2 (0.39) | NPC1RAB9AALDH1A1PKMKDM4E | |
| SCHEMBL10574691 | 0.86 | KDM4E (0.43) | NPC1SMN1; SMN2RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264109-A1 | Platinum complex, process for preparing same and antitumor agent | TORAY INDUSTRIES, INC. (JP) | 1988-04-20 | — | — | EP | claimed |
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |