Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970570 | 0.69 | BACE1 (0.43) | CYP2C9BLMPMP22CACNA1FALDH1A1 | |
| SCHEMBL2308362 | 0.68 | GRIN1 (0.51) | CYP2C9BLMPMP22CACNA1FALDH1A1 | |
| Hydrochloric Acid SCHEMBL29616133 | 0.67 | GRIN1 (0.50) | CYP2C9BLMPMP22CACNA1FALDH1A1 | |
| SCHEMBL10576467 | 0.66 | BACE1 (0.43) | KMT2AMEN1CYP1A2POLBTSHR | |
| SCHEMBL10576643 | 0.66 | BACE1 (0.39) | ALDH1A1KCNH2TSHRLMNAGRIN1 | |
| SCHEMBL7154238 | 0.65 | KMT2A (0.50) | CYP2C9BLMPMP22CACNA1FALDH1A1 | |
| SCHEMBL15657386 | 0.65 | CFTR (0.45) | CYP2C9BLMPMP22CACNA1FALDH1A1 | |
| SCHEMBL10575710 | 0.65 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAGRIN1GRIN2A | |
| Phosphoric Acid SCHEMBL28359864 | 0.63 | BACE1 (0.38) | CYP2C9BLMPMP22CACNA1FALDH1A1 | |
| SCHEMBL10604466 | 0.62 | CNR1 (0.35) | ALDH1A1GRIN1GRIN2ABACE1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746738-A | SKIN THICKENERS | WELLA AKTIENGESELLSCHAFT (DE) | 1988-05-24 | — | — | US | claimed |
| EP-0116318-B1 | TETRAHYDRO-1,3-THIAZINE-2,4-DIONES, THEIR USE AND AGENTS CONTAINING THESE COMPOUNDS FOR THE TREATMENT OF THE SKIN | Wella Aktiengesellschaft (DE) | 1988-03-02 | — | — | EP | claimed |
| EP-0116318-A1 | Tetrahydro-1,3-thiazine-2,4-diones, their use and agents containing these compounds for the treatment of the skin | Wella Aktiengesellschaft (DE) | 1984-08-22 | — | — | EP | claimed |
| WO-1984003041-A1 | TETRAHYDRO-1,3-THIAZIN-2,4-DIONE, UTILIZATION THEREOF AND SKIN TREATING AGENTS CONTAINING SAID COMPOUND | WELLA AG (DE) | 1984-08-16 | — | — | WO | claimed |
| US-4883652-A | THICKEN EPIDERMIS, PROTECTIVE COATING, ANTIAGING | WELLA AKTIENGESELLSCHAFT (DE) | 1989-11-28 | — | — | US | disclosed |
| US-4746738-A | SKIN THICKENERS | WELLA AKTIENGESELLSCHAFT (DE) | 1988-05-24 | — | — | US | disclosed |
| EP-0116318-B1 | TETRAHYDRO-1,3-THIAZINE-2,4-DIONES, THEIR USE AND AGENTS CONTAINING THESE COMPOUNDS FOR THE TREATMENT OF THE SKIN | Wella Aktiengesellschaft (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0116318-A1 | Tetrahydro-1,3-thiazine-2,4-diones, their use and agents containing these compounds for the treatment of the skin | Wella Aktiengesellschaft (DE) | 1984-08-22 | — | — | EP | disclosed |