Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.68 |
| ▸ | PDE4A | P27815 | 8/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501340 | 0.87 | ADORA2B (0.74) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL31061426 | 0.87 | ADORA2B (1.00) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL3108328 | 0.85 | ADORA2B (0.78) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5400933 | 0.83 | PDE4A (0.91) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL4202952 | 0.82 | PDE4A (0.75) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL515564 | 0.82 | ADORA2A (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7738361 | 0.81 | PDE4A (0.73) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL21381263 | 0.80 | ADORA2B (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL3116806 | 0.80 | ADORA2B (1.00) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5006812 | 0.79 | ADORA2B (0.92) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883801-A | Xanthine derivative pest control agents | THE GENERAL HOSPITAL CORPORATION (US) | 1989-11-28 | — | — | US | claimed |
| EP-0193599-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-09-10 | — | — | EP | claimed |
| WO-1986001724-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-03-27 | — | — | WO | claimed |
| US-4883801-A | Xanthine derivative pest control agents | THE GENERAL HOSPITAL CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |