Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 1.00 |
| ▸ | PDE4A | P27815 | 7/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.68 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.60 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.60 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061426 | 0.92 | ADORA2B (1.00) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL3108328 | 0.88 | ADORA2B (0.78) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL7453870 | 0.86 | ADORA2B (1.00) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL8656191 | 0.85 | ADORA2B (0.97) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL27652257 | 0.81 | PDE4A (0.79) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL7109948 | 0.81 | PDE4A (1.00) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL7604273 | 0.81 | ADORA2B (0.72) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL21381258 | 0.80 | PDE4A (0.92) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL16058829 | 0.80 | PDE4A (0.77) | ADORA2BADORA3PDE4APDE4BPDE4C | |
| SCHEMBL7603135 | 0.80 | ADORA2B (0.70) | ADORA2BADORA3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315438-A | Transdermal drug delivery system | 爱肤柔生命科学公司 | 2020-06-19 | — | — | CN | claimed |
| CN-113332292-A | 6, 7-dihydro-5H-pyrazolo [5,1-b ] [1,3] oxazine-2-carboxamide compounds | 辉瑞公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-108699080-B | 6, 7-dihydro-5H-pyrazolo [5,1-b ] [1,3] oxazine-2-carboxamide compounds | 辉瑞公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-107595793-B | Self-regulated release of active pharmaceutical ingredients | 阿库拉制药公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-107406445-B | Cyclopropylbenzofuranyl pyridopyrazine diones | 辉瑞公司 | 2019-12-24 | — | — | CN | disclosed |
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION | 2010-07-15 | — | — | US | disclosed |
| EP-1912992-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SmithKline Beecham Corporation (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017262-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179128-A1 | XANTHINE DERIVATIVES AS SELECTIVE HM74A AGONISTS | XDH, GPR84, GPR88 | ADORA2B 111/4885ADORA3 61/4885PDE4A 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.