Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523462 | 0.78 | GAA (0.53) | ADORA2BADORA2ACYP3A4KMT2AGAA | |
| SCHEMBL4551429 | 0.76 | KDM5A (0.48) | ADORA2BADORA2AKMT2AROCK2CMA1 | |
| SCHEMBL18901219 | 0.74 | ROCK2 (0.56) | KMT2AGAAKDM4EMEN1LMNA | |
| SCHEMBL16377261 | 0.72 | ROCK2 (0.63) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL29507760 | 0.69 | CYP3A4 (0.62) | CYP3A4KMT2AGAAKDM4ELMNA | |
| SCHEMBL6695468 | 0.69 | CYP3A4 (0.62) | CYP3A4KMT2AGAAKDM4ELMNA | |
| SCHEMBL3361253 | 0.69 | MAOA (0.50) | KMT2AGAAKDM4EMEN1LMNA | |
| SCHEMBL16377262 | 0.69 | ROCK2 (0.64) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL11498958 | 0.69 | MEN1 (0.48) | KMT2AGAAKDM4EMEN1LMNA | |
| SCHEMBL9778174 | 0.65 | CYP3A4 (0.50) | ADORA2BADORA2ACYP3A4KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |