Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14692503 | 0.85 | ADORA2B (0.53) | GAAPLK1APOBEC3GKDM4ECYP3A4 | |
| SCHEMBL29507760 | 0.85 | CYP3A4 (0.62) | GAAPLK1APOBEC3GKDM4ECYP3A4 | |
| SCHEMBL6695468 | 0.85 | CYP3A4 (0.62) | GAAPLK1APOBEC3GKDM4ECYP3A4 | |
| SCHEMBL6454733 | 0.84 | CNR2 (0.56) | PLK1APOBEC3GKDM4EMAPTALDH1A1 | |
| SCHEMBL9709253 | 0.80 | ALDH1A1 (0.58) | GAAPLK1APOBEC3GMEN1KMT2A | |
| SCHEMBL30493502 | 0.80 | ALDH1A1 (0.58) | GAAPLK1APOBEC3GMEN1KMT2A | |
| SCHEMBL146503 | 0.79 | CYP1A2 (0.56) | GAAAPOBEC3GKDM4EMAPTCYP3A4 | |
| SCHEMBL10577331 | 0.78 | ADORA2B (0.44) | GAAPLK1APOBEC3GKDM4EMAPT | |
| SCHEMBL24031109 | 0.78 | HDAC1 (0.77) | KDM4EMAPTSMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL4593193 | 0.75 | HSP90AA1 (0.46) | GAAPLK1APOBEC3GKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002990-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED SUBSTITUTED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |