Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574451 | 0.70 | FAAH (0.38) | TSHR | |
| SCHEMBL10574455 | 0.70 | FAAH (0.38) | TSHR | |
| SCHEMBL10577941 | 0.70 | PAX8 (0.34) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL9765450 | 0.67 | MEN1 (0.33) | KMT2A | |
| SCHEMBL10574736 | 0.66 | MAPT (0.30) | HTT | |
| SCHEMBL9838117 | 0.64 | FAAH (0.33) | KMT2A | |
| SCHEMBL11863841 | 0.63 | ALDH1A1 (0.47) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL10576454 | 0.62 | PDE4B (0.34) | — | |
| SCHEMBL10576457 | 0.62 | PDE4B (0.34) | — | |
| SCHEMBL9127507 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-4880933-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | disclosed |