SCHEMBL1057915

SCHEMBL1057915

CSc1cc(O)c2ccccc2c1SC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
TRPM4 Q8TD43 1/20 0.42
IDO1 P14902 3/20 0.41
MAPT P10636 5/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 2/20 0.39
POLB P06746 2/20 0.39
MCL1 Q07820 2/20 0.39
NSD2 O96028 1/20 0.39
EP300 Q09472 3/20 0.38
TP53 P04637 2/20 0.36
GAA P10253 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
NQO2 P16083 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1058386 0.81 LMNA (0.34) LMNAHTTMAPTKMT2AKDM4E
SCHEMBL28480149 0.73 PTPN22 (0.41) MAPTKMT2AKDM4EMEN1TP53
SCHEMBL7199139 0.72 IDO1 (0.59) LMNAHTTIDO1MAPTEP300
SCHEMBL7619563 0.72 CYP1A2 (0.40) LMNAHTTIDO1MAPTKMT2A
SCHEMBL9985255 0.72 MEN1 (0.38) LMNAMAPTKMT2AMEN1TP53
SCHEMBL14283780 0.67 ALOX15 (0.40) LMNAMAPTKMT2AKDM4EMEN1
SCHEMBL1057369 0.67 CYP2A6 (0.46) MAPTKMT2AMEN1HSD17B10HPGD
SCHEMBL30357700 0.67 CYP2A6 (0.46) MAPTKMT2AMEN1HSD17B10HPGD
SCHEMBL23957908 0.67 HPRT1 (0.54) LMNAMAPTKMT2AMEN1TP53
SCHEMBL9986069 0.66 MEN1 (0.36) LMNAMAPTKMT2AMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11525067-B2 Modification method of substrate surface, and composition and polymer JSR CORPORATION (JP) 2022-12-13 US disclosed
US-20220259741-A1 COMPOSITION, METHOD OF PRODUCING SUBSTRATE, AND POLYMER JSR CORPORATION (JP) 2022-08-18 US disclosed
US-20220089809-A1 COMPOSITION, METHOD OF PRODUCING SUBSTRATE, AND POLYMER JSR CORPORATION (JP) 2022-03-24 US disclosed
WO-2021095766-A1 COMPOSITION, PRODUCTION METHOD FOR SUBSTRATE, AND POLYMER JSR株式会社 2021-05-20 WO disclosed
WO-2020250783-A1 COMPOSITION, METHOD FOR PRODUCING SUBSTRATE, AND POLYMER JSR株式会社 2020-12-17 WO disclosed
CN-106909028-B Photosensitive resin composition, protective film and liquid crystal display element 奇美实业股份有限公司 2020-06-05 CN disclosed
US-20200087530-A1 MODIFICATION METHOD OF SUBSTRATE SURFACE, AND COMPOSITION AND POLYMER JSR CORPORATION (JP) 2020-03-19 US disclosed
CN-104950580-B Photosensitive polysiloxane composition and application thereof 奇美实业股份有限公司 2020-01-03 CN disclosed
WO-2019193941-A1 METHOD OF FORMING CURED FILM AND CURABLE COMPOSITION JSR株式会社 2019-10-10 WO disclosed
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed
US-20170168390-A1 PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-15 US disclosed
EP-1662322-B1 Positive type photo-sensitive siloxane composition, curing film formed by the composition and device with the curing film TORAY INDUSTRIES (JP) 2017-01-11 EP disclosed
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION FUJIFILM CORPORATION (JP) 2016-12-29 US disclosed
US-20160216604-A1 COLORED COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-07-28 US disclosed
US-20160054616-A1 ARRAY SUBSTRATE, LIQUID CRYSTAL DISPLAY ELEMENT, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2016-02-25 US disclosed
US-8486604-B2 Positive-type radiation-sensitive composition, cured film, interlayer insulating film, method of forming interlayer insulating film, display device, and siloxane polymer for forming interlayer insulating film JSR CORPORATION (JP) 2013-07-16 US disclosed
US-20110008730-A1 POSITIVE-TYPE RADIATION-SENSITIVE COMPOSITION, CURED FILM, INTERLAYER INSULATING FILM, METHOD OF FORMING INTERLAYER INSULATING FILM, DISPLAY DEVICE, AND SILOXANE POLYMER FOR FORMING INTERLAYER INSULATING FILM JSR CORPORATION (JP) 2011-01-13 US disclosed
US-7374856-B2 Positive type photo-sensitive siloxane composition, cured film formed from the composition and device incorporating the cured film TORAY INDUSTRIES, INC. (JP) 2008-05-20 US disclosed
US-20060115766-A1 Positive type photo-sensitive siloxane composition, cured film formed from the composition and device incorporating the cured film TORAY INDUSTRIES, INC. (JP) 2006-06-01 US disclosed
EP-1662322-A2 Positive type photo-sensitive siloxane composition, curing film formed by the composition and device with the curing film TORAY INDUSTRIES, INC. (JP) 2006-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION O60361, WDR12, SEM1 LMNA 3847/4885HTT 1475/4885TRPM4 2163/4885
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 LMNA 3847/4885HTT 1475/4885TRPM4 2163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.