Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30357700 | 0.90 | CYP2A6 (0.46) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL1057369 | 0.90 | CYP2A6 (0.46) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL23957890 | 0.81 | HSD17B10 (0.41) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL10781864 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TSHRTDP1CYP2A6 | |
| SCHEMBL11908113 | 0.77 | CYP2A6 (0.50) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL1955362 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRTDP1CYP2A6 | |
| SCHEMBL23027425 | 0.74 | HSD17B10 (0.50) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL13021634 | 0.74 | TSHR (0.56) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL25510 | 0.73 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TSHRTDP1 | |
| Chrysene SCHEMBL384031 | 0.73 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332011-A1 | TOTAL SYNTHESIS OF PROSTAGLANDIN J NATURAL PRODUCTS BY TEREORETENTIVE METATHESIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332011-A1 | TOTAL SYNTHESIS OF PROSTAGLANDIN J NATURAL PRODUCTS BY TEREORETENTIVE METATHESIS | PTGES, PTGES2, PTGIS | HPRT1 2136/4885ALDH1A1 3137/4885HSD17B10 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.