SCHEMBL10580750

SCHEMBL10580750

CC(=O)CC(=O)Nc1cccc(O)c1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
CYP1A2 P05177 2/20 0.68
NLRP3 Q96P20 10/20 0.61
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KDM4E B2RXH2 1/20 0.58
CYP2C19 P33261 1/20 0.58
HIF1A Q16665 1/20 0.58
MAPT P10636 2/20 0.57
RAB9A P51151 3/20 0.55
NPSR1 Q6W5P4 1/20 0.55
MAPK1 P28482 1/20 0.55
NPC1 O15118 1/20 0.54
POLB P06746 1/20 0.53
NR4A1 P22736 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31570060 1.00 ALDH1A1 (0.68) ALDH1A1CYP1A2NLRP3MEN1KMT2A
SCHEMBL5142374 0.89 ALDH1A1 (0.66) ALDH1A1CYP1A2NLRP3MEN1KMT2A
SCHEMBL8752439 0.89 MEN1 (0.66) ALDH1A1CYP1A2MEN1KMT2AKDM4E
SCHEMBL29331181 0.86 ALDH1A1 (0.64) ALDH1A1CYP1A2NLRP3MEN1KMT2A
SCHEMBL127182 0.84 CA1 (0.61) ALDH1A1CYP1A2NLRP3MEN1KMT2A
SCHEMBL11761862 0.84 RAB9A (0.74) ALDH1A1CYP1A2NLRP3MEN1KMT2A
Phenol SCHEMBL11586527 0.84 MAPT (0.74) ALDH1A1CYP1A2MEN1KMT2AKDM4E
SCHEMBL6360996 0.84 RAB9A (0.69) ALDH1A1CYP1A2NLRP3MEN1KMT2A
SCHEMBL18530334 0.82 KMT2A (0.58) ALDH1A1CYP1A2NLRP3MEN1KMT2A
SCHEMBL4858118 0.82 HSD17B10 (0.68) ALDH1A1CYP1A2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4385147-A Stabilization of chlorine-containing thermoplastics with m-aminophenol derivatives CIBA-GEIGY CORPORATION (US) 1983-05-24 US claimed
US-4137080-A POLYFUNCTIONAL COUPLER AND DEVELOPER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-01-30 US claimed
CN-101408722-B Photosensitive micro-capsule and preparing method thereof UNIV BEIJING CHEMICAL 2011-01-19 CN disclosed
CN-101408722-A Photosensitive micro-capsule and preparing method thereof UNIV BEIJING CHEMICAL (CN) 2009-04-15 CN disclosed
EP-0305873-A2 Positive photosensitive composition and photosensitive registration material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-08 EP disclosed
EP-0048222-B1 STABILISATION OF THERMOPLASTICS THAT CONTAIN CHLORINE WITH M-AMINO PHENOLS CIBA-GEIGY AG (CH) 1984-12-27 EP disclosed
US-4385147-A Stabilization of chlorine-containing thermoplastics with m-aminophenol derivatives CIBA-GEIGY CORPORATION (US) 1983-05-24 US disclosed
US-4370397-A Presensitized plastic card, tamperproof identification card prepared therefrom, and process for manufacture of tamperproof identification card RHONE-POULENC SYSTEMES (FR) 1983-01-25 US disclosed
EP-0048222-A1 Stabilisation of thermoplastics that contain chlorine with m-amino phenols CIBA-GEIGY AG (CH) 1982-03-24 EP disclosed
US-4131468-A ROUGH ACRYLIC POLYMER COATING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-12-26 US disclosed
US-4036633-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES ROUSSEL-UCLAF (FR) 1977-07-19 US disclosed