SCHEMBL127182

SCHEMBL127182

NCC(=O)Nc1cccc(O)c1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
ALDH1A1 P00352 1/20 0.59
CYP1A2 P05177 1/20 0.59
NLRP3 Q96P20 11/20 0.58
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
HDAC4 P56524 1/20 0.55
TERT O14746 1/20 0.53
MAPT P10636 1/20 0.52
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13233238 0.87 HDAC4 (0.65) ALDH1A1CYP1A2NLRP3KMT2AMEN1
SCHEMBL5142374 0.86 ALDH1A1 (0.66) ALDH1A1CYP1A2NLRP3KMT2AMEN1
Hydrochloric Acid SCHEMBL19747848 0.86 CA1 (0.67) CA1CA2KMT2AMEN1TERT
SCHEMBL18530334 0.84 KMT2A (0.58) ALDH1A1CYP1A2NLRP3KMT2AMEN1
SCHEMBL31570060 0.84 ALDH1A1 (0.68) ALDH1A1CYP1A2NLRP3KMT2AMEN1
SCHEMBL10580750 0.84 ALDH1A1 (0.68) ALDH1A1CYP1A2NLRP3KMT2AMEN1
SCHEMBL9799670 0.83 ALDH1A1 (0.61) ALDH1A1CYP1A2NLRP3KMT2AMEN1
Hydrochloric Acid SCHEMBL15284015 0.82 HDAC4 (0.67) ALDH1A1CYP1A2NLRP3KMT2AMEN1
SCHEMBL14202768 0.81 ALDH1A1 (0.59) ALDH1A1CYP1A2NLRP3KMT2AMEN1
SCHEMBL441932 0.81 HDAC4 (0.67) ALDH1A1CYP1A2NLRP3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 862 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105916482-A Gradual hair color compositions and methods of use thereof 酷姆国际公司 2016-08-31 CN claimed
EP-0850636-B2 Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition OREAL (FR) 2013-11-20 EP claimed
EP-1473025-B1 Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer OREAL (FR) 2012-03-28 EP claimed
EP-1493426-B1 Dyeing composition comprising a developer, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone OREAL (FR) 2009-08-12 EP claimed
EP-1348422-B1 Oxidation dyeing composition for keratin fibers comprising 2-chloro-6-methyl-3-aminophenol and an oxidation base, and dyeing method OREAL (FR) 2009-04-29 EP claimed
EP-1047376-B2 KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME OREAL (FR) 2009-03-18 EP claimed
EP-1129689-B1 Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing OREAL (FR) 2008-07-09 EP claimed
EP-1410788-B1 Oxidation dyeing composition for keratinous fibres comprising 2-chloro 6 methyl 3-aminophenol, an oxidation base and an additional coupler, and dyeing method OREAL (FR) 2006-05-10 EP claimed
EP-1621185-A1 Hair dyeing composition comprising an elastomeric film-forming polymer and an oxidation dye precursor L'OREAL (FR) 2006-02-01 EP claimed
EP-1057471-B1 Composition for oxidative dying of keratinous fibres and dying process therewith OREAL (FR) 2005-05-11 EP claimed
EP-0850636-A1 Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition L'OREAL (FR) 1998-07-01 EP claimed
EP-0790818-A1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME L'OREAL (FR) 1997-08-27 EP claimed
WO-1997015271-A1 METHOD FOR OXIDATION DYEING KERATIN FIBRES AND COMPOSITION THEREFOR L'OREAL (FR) 1997-05-01 WO claimed
WO-1997011673-A1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME L'OREAL (FR) 1997-04-03 WO claimed
EP-0733356-B1 Composition for dyeing keratinous fibres and dyeing process using the said composition OREAL (FR) 1997-03-26 EP claimed
EP-0733356-A1 Composition for dyeing keratinous fibres L'OREAL (FR) 1996-09-25 EP claimed
EP-0728463-A1 Composition for oxidation dyeing of keratinous fibers comprising at least two oxidation bases and an indole coupleur and process for dyeing L'OREAL (FR) 1996-08-28 EP claimed
EP-0728466-A1 Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process L'OREAL (FR) 1996-08-28 EP claimed
EP-0366542-B1 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES L'OREAL (FR) 1993-07-14 EP claimed
EP-0366542-A1 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres L'OREAL (FR) 1990-05-02 EP claimed