Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838818 | 0.75 | LMNA (0.45) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL2087244 | 0.75 | LMNA (0.45) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL11340035 | 0.73 | FDPS (0.48) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL8623833 | 0.69 | LMNA (0.45) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL16216680 | 0.69 | LMNA (0.45) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL335957 | 0.68 | — | — | |
| SCHEMBL97568 | 0.65 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL4147247 | 0.65 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL21382633 | 0.65 | — | — | |
| SCHEMBL4649888 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4828766-A | FROM 1-/ACYL/-ETHANE-1,1-DIPHOSPHONIC ACID | BENCKISER-KNAPSACK GMBH (DE) | 1989-05-09 | — | — | US | disclosed |